Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

Abstract Background Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. Methods Infant (2 weeks old) and adult (6 weeks old) mice were submitted to sepsis by i...

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Bibliographic Details
Main Authors: David F. Colón, Carlos W. Wanderley, Marcelo Franchin, Camila M. Silva, Carlos H. Hiroki, Fernanda V. S. Castanheira, Paula B. Donate, Alexandre H. Lopes, Leila C. Volpon, Silvia K. Kavaguti, Vanessa F. Borges, Cesar A. Speck-Hernandez, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Jose C. Alves-Filho, Foo Y. Liew, Fernando Q. Cunha
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Critical Care
Subjects:
Infant
Sepsis
Susceptibility
Neutrophil extracellular traps
Padi4
Online Access:http://link.springer.com/article/10.1186/s13054-019-2407-8

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http://link.springer.com/article/10.1186/s13054-019-2407-8

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