The Multifunctional Protein BAG3

The Multifunctional Protein BAG3

The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy; binds to B-cell lymphoma 2, resulting in inhibition...

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Bibliographic Details
Main Authors: Valerie D. Myers, MS, Joseph M. McClung, PhD, JuFang Wang, MD, Farzaneh G. Tahrir, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Christopher H. Kontos, MD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:JACC: Basic to Translational Science
Subjects:
autophagy
apoptosis
BAG3
heart failure
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X17302607

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http://www.sciencedirect.com/science/article/pii/S2452302X17302607

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