Synthesis and Cytotoxicity Testing of New Amido-Substituted Triazolopyrrolo[2,1-<em>c</em>][1,4]benzodiazepine (PBDT) Derivatives

Synthesis and Cytotoxicity Testing of New Amido-Substituted Triazolopyrrolo[2,1-<em>c</em>][1,4]benzodiazepine (PBDT) Derivatives

A series of amido-substituted triazolopyrrolo[2,1-<em>c</em>][1,4]benzodiazepine (<strong>PBDT</strong>) derivatives was synthesized from isatoic anhydride, and their cytotoxicity against the MRC-5 and Mahlavu cell lines was evaluated. The resu...

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Bibliographic Details
Main Authors: Bo-Ying Bao, Chia-Hao Su, Min-Chiau Laiu, Khagga Mukkanti, Srinivas Pusuluri, Chi-Fen Chang, Kumaraswamy Sorra, Ta-Hsien Chuang
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Molecules
Subjects:
triazolopyrrolobenzodiazepine
Lawesson’s reagent
cytotoxicity
Mahlavu celles
MRC-5 cells
Online Access:http://www.mdpi.com/1420-3049/17/8/8762

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http://www.mdpi.com/1420-3049/17/8/8762

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