Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.

Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.

Endoplasmic reticulum stress (ERS)-mediated autophagy is indispensable for modulation of replication and pathogenesis of numerous mammalian viruses. We have previously shown that classical swine fever virus (CSFV) infection induces ERS-mediated autophagy for maintaining viral replication both in viv...

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Bibliographic Details
Main Authors: Erpeng Zhu, Huawei Wu, Wenxian Chen, Yuwei Qin, Jiameng Liu, Shuangqi Fan, Shengming Ma, Keke Wu, Qian Mao, Chaowei Luo, Yixian Qin, Lin Yi, Hongxing Ding, Mingqiu Zhao, Jinding Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
autophagy
classical swine fever virus
endoplasmic reticulum stress
ire1
perk
proinflammatory cytokines
virus replication
Online Access:http://dx.doi.org/10.1080/21505594.2020.1845040

Internet

http://dx.doi.org/10.1080/21505594.2020.1845040

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