The PPARα Agonist Fenofibrate Reduces Prepulse Inhibition Disruption in a Neurodevelopmental Model of Schizophrenia

Oxidative stress has been implicated in neurodevelopmental theories of schizophrenia. Antioxidant Peroxysome Proliferator-Activated Receptors α (PPARα) agonist fenofibrate has neuroprotective properties and could reverse early preclinical infringements that could trigger the illness. We have evalua...

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Bibliographic Details
Main Authors: Benjamin Rolland, Kevin Marche, Olivier Cottencin, Régis Bordet
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Schizophrenia Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/839853