Fish oil-derived long-chain n-3 polyunsaturated fatty acids reduce expression of M1-associated macrophage markers in an ex vivo adipose tissue culture model, in part through adiponectin

Fish oil-derived long-chain n-3 polyunsaturated fatty acids reduce expression of M1-associated macrophage markers in an ex vivo adipose tissue culture model, in part through adiponectin

Adipose tissue (AT) macrophages (ATM) play a key role in obesity-associated pathologies, and their phenotype can be influenced by the local tissue microenvironment. Interestingly, long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA) and the LC n-3 PUFA-upregulated adipokine, adiponectin (Ad), ma...

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Bibliographic Details
Main Authors: Anna A. De Boer, Jennifer M. Monk, Danyelle M. Liddle, Krista A. Power, David W.L. Ma, Lindsay E. Robinson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Nutrition
Subjects:
Adiponectin
Adipose Tissue
Obesity
lipopolysaccharide
n-3 polyunsaturated fatty acids
M1 macrophage
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnut.2015.00031/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnut.2015.00031/full

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