DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

Abstract Background One of the major challenges in obesity treatment is to explain the high variability in the individual’s response to specific dietary and physical activity interventions. With this study, we tested the hypothesis that specific DNA methylation changes reflect individual responsiven...

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Bibliographic Details
Main Authors: Maria Keller, Anat Yaskolka Meir, Stephan H. Bernhart, Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Gal Tsaban, Hila Zelicha, Lydia Hopp, Luise Müller, Kerstin Rohde, Yvonne Böttcher, Peter F. Stadler, Michael Stumvoll, Matthias Blüher, Peter Kovacs, Iris Shai
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Genome Medicine
Subjects:
Lifestyle intervention
Weight-loss
Epigenetics
DNA methylation
Gene
Online Access:http://link.springer.com/article/10.1186/s13073-020-00794-7

Internet

http://link.springer.com/article/10.1186/s13073-020-00794-7

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