Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14

Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14

Spinocerebellar ataxia 27 (SCA27) is a recently described syndrome characterized by impaired cognitive abilities and a slowly progressive ataxia. SCA27 is caused by an autosomal dominant missense mutation in Fibroblast Growth Factor 14 (FGF14). Mice lacking FGF14 (Fgf14−/− mice) have impaired sensor...

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Bibliographic Details
Main Authors: David F. Wozniak, Maolei Xiao, Lin Xu, Kelvin A. Yamada, David M. Ornitz
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neurobiology of Disease
Subjects:
FGF14
FGF Homologous Factors
Hippocampus
Learning and Memory
LTP
Behavior
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003056

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http://www.sciencedirect.com/science/article/pii/S0969996106003056

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