Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer

Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer

<p>Abstract</p> <p>Background</p> <p>We analyzed the influence of 8 germinal polymorphisms of candidate genes potentially related to EGFR signalling (<it>EGFR</it>, <it>EGF</it>, <it>CCND1</it>) or antibody-directed cell cytotoxicity...

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Main Authors: Dahan Laetitia, Norguet Emmanuelle, Etienne-Grimaldi Marie-Christine, Formento Jean-Louis, Gasmi Mohamed, Nanni Isabelle, Gaudart Jean, Garcia Stéphane, Ouafik L'Houcine, Seitz Jean-François, Milano Gérard
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Cancer
Subjects:
EGFR inhibitors
cetuximab
clinical outcome
colorectal cancer
polymorphisms
Online Access:http://www.biomedcentral.com/1471-2407/11/496

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http://www.biomedcentral.com/1471-2407/11/496

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