Addressing Patient Specificity in the Engineering of Tumor Models

Cancer treatment is challenged by the heterogeneous nature of cancer, where prognosis depends on tumor type and disease stage, as well as previous treatments. Optimal patient stratification is critical for the development and validation of effective treatments, yet pre-clinical model systems are lac...

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Bibliographic Details
Main Authors: Laura J. Bray, Dietmar W. Hutmacher, Nathalie Bock
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00217/full