Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer

<p>Abstract</p> <p>Background</p> <p>Considerable variation in intravenous 5-fluorouracil (5-FU) metabolism can occur due to the wide range of dihydropyrimidine dehydrogenase (DPD) enzyme activity, which can affect both tolerability and efficacy. The oral fluoropyrimidi...

Full description

Bibliographic Details
Main Authors: Calais Gilles, Burtin Pascal, Carrie Christian, Salemkour Augustin, Vendrely Véronique, Chevelle Christian, Vié Brigitte, Martin Laurent, Leduc Bernard, Cellier Patrice, Campion Loïc, Boisdron-Celle Michèle, Morel Alain, Berger Virginie, Gamelin Erick
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/98