Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells.

Thiamin (vitamin B1), a member of the water-soluble family of vitamins, is essential for normal cellular functions; its deficiency results in oxidative stress and mitochondrial dysfunction. Pancreatic acinar cells (PAC) obtain thiamin from the circulation using a specific carrier-mediated process me...

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Bibliographic Details
Main Authors: Padmanabhan Srinivasan, Edwin C Thrower, Gopalakrishnan Loganathan, A N Balamurugan, Veedamali S Subramanian, Fred S Gorelick, Hamid M Said
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669105?pdf=render