Juglone Suppresses LPS-induced Inflammatory Responses and NLRP3 Activation in Macrophages

The NLRP3 (NACHT, LRR and PYD domains-containing protein 3) inflammasome has been implicated in a variety of diseases, including atherosclerosis, neurodegenerative diseases, and infectious diseases. Thus, inhibitors of NLRP3 inflammasome have emerged as promising approaches to treat inflammation-rel...

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Bibliographic Details
Main Authors: Nam-Hun Kim, Hong-Ki Kim, Ji-Hak Lee, Seung-Il Jo, Hye-Min Won, Gyeong-Seok Lee, Hyoun-Su Lee, Kung-Woo Nam, Wan-Jong Kim, Man-Deuk Han
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/13/3104