Pro-osteoporotic miR-320a impairs osteoblast function and induces oxidative stress.

MicroRNAs (miRNAs) are important regulators of many cellular processes, including the differentiation and activity of osteoblasts, and therefore, of bone turnover. MiR-320a is overexpressed in osteoporotic bone tissue but its role in osteoblast function is unknown. In the present study, functional a...

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Bibliographic Details
Main Authors: Laura De-Ugarte, Susana Balcells, Xavier Nogues, Daniel Grinberg, Adolfo Diez-Perez, Natalia Garcia-Giralt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208131