Single-Cell Analyses Identify Dysfunctional CD16+ CD8 T Cells in Smokers

Single-Cell Analyses Identify Dysfunctional CD16+ CD8 T Cells in Smokers

Summary: Tobacco smoke exposure contributes to the global burden of communicable and chronic diseases. To identify the immune cells affected by smoking, we use single-cell RNA sequencing on peripheral blood from smokers and nonsmokers. Transcriptomes reveal a subpopulation of FCGR3A (CD16)-expressin...

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Bibliographic Details
Main Authors: Suzanne N. Martos, Michelle R. Campbell, Oswaldo A. Lozoya, Xuting Wang, Brian D. Bennett, Isabel J.B. Thompson, Ma Wan, Gary S. Pittman, Douglas A. Bell
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Cell Reports Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379120300707

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http://www.sciencedirect.com/science/article/pii/S2666379120300707

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