Ex vivo Demonstration of Functional Deficiencies in Popliteal Lymphatic Vessels From TNF-Transgenic Mice With Inflammatory Arthritis

Ex vivo Demonstration of Functional Deficiencies in Popliteal Lymphatic Vessels From TNF-Transgenic Mice With Inflammatory Arthritis

Background: Recent studies demonstrated lymphangiogenesis and expansion of draining lymph nodes during chronic inflammatory arthritis, and lymphatic dysfunction associated with collapse of draining lymph nodes in rheumatoid arthritis (RA) patients and TNF-transgenic (TNF-Tg) mice experiencing arthri...

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Bibliographic Details
Main Authors: Joshua P. Scallan, Echoe M. Bouta, Homaira Rahimi, H. Mark Kenney, Christopher T. Ritchlin, Michael J. Davis, Edward M. Schwarz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
inflammatory arthritis
lymphatic vessels
ex vivo analysis
mouse models
vessel contraction
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.745096/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.745096/full

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