Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

A bioactive compound isolated from the stem extract of Aristolochia sprucei through High Performance Liquid Chromatography (HPLC) was identified via Nuclear Magnetic Resonance (NMR) as the aristolochic acid (AA). This compound showed an inhibitory effect over the myotoxic activity of Bothrops jarara...

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Bibliographic Details
Main Authors: Isela I. González Rodríguez, Aleff F. Francisco, Leandro S. Moreira-Dill, Aristides Quintero, César L.S. Guimarães, Carlos A.H. Fernandes, Agnes A.S. Takeda, Fernando B. Zanchi, Cléopatra A.S. Caldeira, Paulo S. Pereira, Marcos R.M. Fontes, Juliana P. Zuliani, Andreimar M. Soares
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Toxicon: X
Subjects:
Aristolochia sprucei
Aristolochic acid
Antivenom medicinal plants
Myotoxin inhibitor
Snake venoms
Phospholipases A2
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171020300278

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http://www.sciencedirect.com/science/article/pii/S2590171020300278

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