Malignant transformation of a rat fibroma by the treatment with an anti-fibrosing drug: CY-168F (Plastenan)

Fifteen albino (Sprague Dawley) rats with subcutaneous transplanted fibromas was used in the present study. The tumour was formed by typical fibroblasts in a dense collagen matrix and was provenient from a fibroma that appeared spontaneously in an albino rat of the same strain. Ultrastructurally col...

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Bibliographic Details
Main Authors: Sonia G. Andrade, Jean Alexis Grimaud, Eric Tabone, Manoel Barral Netto
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1981-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761981000300003