Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure.

Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure.

The prognosis of acute myeloid leukemia (AML) in elderly (≥65 years) patients is poor and treatment remains non-consensual especially for those who are not eligible for intensive therapies. Our group has shown that in vitro the iron chelator deferasirox (DFX) synergizes with vitamin D (VD) to promot...

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Bibliographic Details
Main Authors: Etienne Paubelle, Florence Zylbersztejn, Sawsaneh Alkhaeir, Felipe Suarez, Céline Callens, Michaël Dussiot, Françoise Isnard, Marie-Thérèse Rubio, Gandhi Damaj, Norbert-Claude Gorin, Jean-Pierre Marolleau, Renato C Monteiro, Ivan C Moura, Olivier Hermine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23840388/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23840388/pdf/?tool=EBI

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