Penicillin‐binding protein PBP2a provides variable levels of protection toward different β‐lactams in Staphylococcus aureus RN4220

Penicillin‐binding protein PBP2a provides variable levels of protection toward different β‐lactams in Staphylococcus aureus RN4220

Abstract Methicillin‐resistant Staphylococcus aureus (MRSA) is resistant to most β‐lactams due to the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity. It has long been known that heterologous expression of the PBP2a‐encoding mecA gene in methicillin‐sensitive S. ...

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Bibliographic Details
Main Authors: Marte Ekeland Fergestad, Gro Anita Stamsås, Danae Morales Angeles, Zhian Salehian, Yngvild Wasteson, Morten Kjos
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:MicrobiologyOpen
Subjects:
mecA
microfluidics
MRSA
time‐lapse microscopy
β‐lactams
Online Access:https://doi.org/10.1002/mbo3.1057

Internet

https://doi.org/10.1002/mbo3.1057

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