Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease

Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease

Abstract Background Senescent astrocytes have been implicated in the aging brain and neurodegenerative disorders, including Parkinson’s disease (PD). Astragaloside IV (AS-IV) is an antioxidant derivative from a traditional Chinese herbal medicine Astragalus membraneaceus Bunge and exerts anti-inflam...

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Bibliographic Details
Main Authors: Mei-Ling Xia, Xia-Hong Xie, Jian-Hua Ding, Ren-Hong Du, Gang Hu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Astragaloside IV
Astrocyte
Cell senescence
Mitophagy
Parkinson’s disease
Online Access:http://link.springer.com/article/10.1186/s12974-020-01791-8

Internet

http://link.springer.com/article/10.1186/s12974-020-01791-8

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