Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge

Sufficient uptake and whole body distribution of vitamin C (ascorbate) is essential for many biochemical processes, including some that are vital for tumor growth and spread. Uptake of ascorbate into cancer cells is modulated by availability, tumor blood flow, tissue diffusion parameters, and ascorb...

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Bibliographic Details
Main Authors: Gabi U. Dachs, Christina Wohlrab, Elisabeth Phillips
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00074/full