A Facile One-Pot Method for Synthesis of 2,4-Dichloroquinoline Derivatives

A facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.

Bibliographic Details
Main Authors: Javad Azizian, Hassan Kefayati, Morteza Mehrdad, Khosrow Jadidi, Yaghob Sarrafi
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2001-06-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
Online Access:http://www.ijcce.ac.ir/article_9981_3d294b1e475c255903f347ff71d890f3.pdf