Chemistry of polyhalogenated nitrobutadienes, 10: Synthesis of highly functionalized heterocycles with a rigid 6-amino-3-azabicyclo[3.1.0]hexane moiety

Chemistry of polyhalogenated nitrobutadienes, 10: Synthesis of highly functionalized heterocycles with a rigid 6-amino-3-azabicyclo[3.1.0]hexane moiety

The nitropolychlorobutadienes 3, 4 are valuable building blocks for various amination and successive heterocyclization products. Nucleophilic substitution reactions of the partially protected, bioactive amines 1, 2 with either vinyl, imidoyl or carbonyl chlorides result in the formation of the enami...

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Bibliographic Details
Main Authors: Viktor A. Zapol’skii, Jan C. Namyslo, Armin de Meijere, Dieter E. Kaufmann
Format: Article
Language:English
Published: Beilstein-Institut 2012-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
isothiazole
nitrochlorobutadiene
nitropyrazole
nucleophilic substitution
pyrimidine
small rings
Online Access:https://doi.org/10.3762/bjoc.8.69

Internet

https://doi.org/10.3762/bjoc.8.69

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