DNA, cell wall and general oxidative damage underlie the tellurite/cefotaxime synergistic effect in Escherichia coli.

The constant emergence of antibiotic multi-resistant pathogens is a concern worldwide. An alternative for bacterial treatment using nM concentrations of tellurite was recently proposed to boost antibiotic-toxicity and a synergistic effect of tellurite/cefotaxime (CTX) was described. In this work, th...

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Bibliographic Details
Main Authors: Roberto C Molina-Quiroz, David E Loyola, Claudia M Muñoz-Villagrán, Raquel Quatrini, Claudio C Vásquez, José M Pérez-Donoso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832599?pdf=render