Computational Modeling of Interstitial Fluid Pressure and Velocity in Non-small Cell Lung Cancer Brain Metastases Treated With Stereotactic Radiosurgery

Computational Modeling of Interstitial Fluid Pressure and Velocity in Non-small Cell Lung Cancer Brain Metastases Treated With Stereotactic Radiosurgery

Background: Early imaging-based treatment response assessment of brain metastases following stereotactic radiosurgery (SRS) remains challenging. The aim of this study is to determine whether early (within 12 weeks) intratumoral changes in interstitial fluid pressure (IFP) and velocity (IFV) estimate...

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Bibliographic Details
Main Authors: Nathaniel Swinburne, Eve LoCastro, Ramesh Paudyal, Jung Hun Oh, Neil K. Taunk, Akash Shah, Kathryn Beal, Behroze Vachha, Robert J. Young, Andrei I. Holodny, Amita Shukla-Dave, Vaios Hatzoglou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neurology
Subjects:
Stereotactic radiosurgery (SRS)
brain metastases from lung cancer
perfusion MRI
computational fluid modeling
interstitial fluid pressure
treatment response
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00402/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00402/full

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