Nuclear entry of hepatitis B virus capsids involves disintegration to protein dimers followed by nuclear reassociation to capsids.

Assembly and disassembly of viral capsids are essential steps in the viral life cycle. Studies on their kinetics are mostly performed in vitro, allowing application of biochemical, biophysical and visualizing techniques. In vivo kinetics are poorly understood and the transferability of the in vitro...

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Bibliographic Details
Main Authors: Birgit Rabe, Mildred Delaleau, Andreas Bischof, Michael Foss, Irina Sominskaya, Paul Pumpens, Christian Cazenave, Michel Castroviejo, Michael Kann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2727048?pdf=render