Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats

Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats

<p>Abstract</p> <p>Background</p> <p>Rabies is known to be lethal in human. Treatment with passive immunity for the rabies is effective only when the patients have not shown the central nerve system (CNS) signs. The blood–brain barrier (BBB) is a complex functional barr...

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Bibliographic Details
Main Authors: Liao Pi-Hung, Yang Hui-Hua, Chou Ping-Tse, Wang Ming-Hseng, Chu Po-Chun, Liu Hao-Li, Chen Li-Kuang
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Biomedical Science
Subjects:
Rabies
Blood–brain barrier
Central nerve system
Cerebrospinal fluid
Occludin
Hypertonic breakdown
Virus-neutralizing monoclonal antibody
Passive immunotherapy
Online Access:http://www.jbiomedsci.com/content/19/1/61

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http://www.jbiomedsci.com/content/19/1/61

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