FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data

FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data

Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein regulation by post-translational modifications (PTMs) is not binary, making methods to quantify the modification extent crucial to understanding...

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Bibliographic Details
Main Authors: Christoph N Schlaffner, Konstantin Kahnert, Jan Muntel, Ruchi Chauhan, Bernhard Y Renard, Judith A Steen, Hanno Steen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
PTM identification
PTM quantification
label-free quantification
peptide modification
modification stoichiometry
mass spectrometry
Online Access:https://elifesciences.org/articles/58783

Internet

https://elifesciences.org/articles/58783

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