FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data
Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein regulation by post-translational modifications (PTMs) is not binary, making methods to quantify the modification extent crucial to understanding...
Main Authors: | Christoph N Schlaffner, Konstantin Kahnert, Jan Muntel, Ruchi Chauhan, Bernhard Y Renard, Judith A Steen, Hanno Steen |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/58783 |
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