Advances of Ribonucleotide Reductase Inhibitors on Cancer

Ribonucleotide reductase (RR) regulates dNTP production, catalyzing the reduction of ribonucleotide into deoxyribonucleotide diphosphate, which is essential in DNA synthesis and cell proliferation. RR overexpression is related with the tumorigenesis and tumor progression. At present, RR inhibitors h...

Full description

Bibliographic Details
Main Authors: WANG An'ge, WU Zhe, WANG Li, QIU Yunqing
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2019-08-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0100.htm