Advances of Ribonucleotide Reductase Inhibitors on Cancer
Ribonucleotide reductase (RR) regulates dNTP production, catalyzing the reduction of ribonucleotide into deoxyribonucleotide diphosphate, which is essential in DNA synthesis and cell proliferation. RR overexpression is related with the tumorigenesis and tumor progression. At present, RR inhibitors h...
Main Authors: | WANG An'ge, WU Zhe, WANG Li, QIU Yunqing |
---|---|
Format: | Article |
Language: | zho |
Published: |
Magazine House of Cancer Research on Prevention and Treatment
2019-08-01
|
Series: | Zhongliu Fangzhi Yanjiu |
Subjects: | |
Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0100.htm |
Similar Items
-
Structure-guided design of anti-cancer ribonucleotide reductase inhibitors
by: Tessianna A. Misko, et al.
Published: (2019-01-01) -
Design and synthesis of potential ribonucleotide reductase enzyme (RNR) inhibitors as antileukemic and/or antiviral 2′-deoxymethylene nucleosides
by: Khairia M. Youssef, et al.
Published: (2015-12-01) -
Herpes simplex ribonucleotide reductase
by: Ingemarson, Rolf
Published: (1989) -
Vaccinia virus ribonucleotide reductase : regulation of the gene products and characterization of the recombinant small subunit protein
by: Howell, Meredith L.
Published: (2013) -
Ribonucleotide reductase inhibitors: a new look at an old target for radiosensitization
by: Tobias eChapman, et al.
Published: (2012-01-01)