Small-Molecule XIAP Inhibitors Enhance γ-Irradiation-Induced Apoptosis in Glioblastoma

Small-Molecule XIAP Inhibitors Enhance γ-Irradiation-Induced Apoptosis in Glioblastoma

Because evasion of apoptosis can cause radioresistance of glioblastoma, there is a need to design rational strategies that counter apoptosis resistance. In the present study, we investigated the potential of targeting the antiapoptotic protein XIAP for the radiosensitization of glioblastoma. Here,...

Full description

Bibliographic Details
Main Authors: Sri Hari Krishna Vellanki, Andreas Grabrucker, Stefan Liebau, Christian Proepper, Adriana Eramo, Veit Braun, Tobias Boeckers, Klaus-Michael Debatin, Simone Fulda
Format: Article
Language:English
Published: Elsevier 2009-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609801309

Internet

http://www.sciencedirect.com/science/article/pii/S1476558609801309

Similar Items