Small-Molecule XIAP Inhibitors Enhance γ-Irradiation-Induced Apoptosis in Glioblastoma
Because evasion of apoptosis can cause radioresistance of glioblastoma, there is a need to design rational strategies that counter apoptosis resistance. In the present study, we investigated the potential of targeting the antiapoptotic protein XIAP for the radiosensitization of glioblastoma. Here,...
Main Authors: | Sri Hari Krishna Vellanki, Andreas Grabrucker, Stefan Liebau, Christian Proepper, Adriana Eramo, Veit Braun, Tobias Boeckers, Klaus-Michael Debatin, Simone Fulda |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-08-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558609801309 |
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