LncRNA Mrhl orchestrates differentiation programs in mouse embryonic stem cells through chromatin mediated regulation

Long non-coding RNAs (lncRNAs) have been well-established to act as regulators and mediators of development and cell fate specification programs. LncRNA Mrhl (meiotic recombination hotspot locus) has been shown to act in a negative feedback loop with WNT signaling to regulate male germ cell meiotic...

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Bibliographic Details
Main Authors: Debosree Pal, C.V. Neha, Utsa Bhaduri, Zenia Zenia, Sangeeta Dutta, Subbulakshmi Chidambaram, M.R.S. Rao
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121000969