Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice

Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice

<p>Abstract</p> <p>Background</p> <p>CD8+ T cells participate in airway hyperresponsiveness (AHR) and allergic pulmonary inflammation that are characteristics of asthma. CXCL10 by binding to CXCR3 expressed preferentially on activated CD8+ T cells, attracts T cells homi...

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Bibliographic Details
Main Authors: Zhou Wexun, Guo Zijian, Huang Kewu, Chen Huaxia, Jiang Lei, Xiang Ruolan, Piao Hongmei, Xiao Yu, Yan Haibo, Lin Yi, Lu Bao, Gao Jinming
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Respiratory Research
Subjects:
chemokine receptor
CXCR3
CD8+ T lymphocyte
airway inflammation
airway hyperresponsiveness
Online Access:http://respiratory-research.com/content/12/1/123

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http://respiratory-research.com/content/12/1/123

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