Suppressive activity of macrolide antibiotics on nitric oxide production by lipopolysaccharide stimulation in mice

Background and aim: Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including n...

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Bibliographic Details
Main Authors: Hajime Terao, Kazuhito Asano, Ken-ichi Kanai, Yoshiyuki Kyo, So Watanabe, Tadashi Hisamitsu, Harumi Suzaki
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/09629350310001599620