Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21

Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21

Abstract Background The mechanism of pancreatic cancer metastasis remains poorly understood. Recently, lncRNA CASC2 has been demonstrated to be a tumor suppressor in various types of cancer. This study aimed to explore the mechanism of CASC2 in the regulation of pancreatic cancer metastasis. Methods...

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Bibliographic Details
Main Authors: Hui Zhang, Xielin Feng, Mingyi Zhang, Aixiang Liu, Lang Tian, Wentao Bo, Haiqing Wang, Yong Hu
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cancer Cell International
Subjects:
CASC2
miR-21
PTEN
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s12935-019-0728-y

Internet

http://link.springer.com/article/10.1186/s12935-019-0728-y

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