The characteristics of determination of BRCA1 and BRCA2 mutations in serous ovarian cancer
Mutations of the BRCA1/BRCA2 genes occur in 15-20% cases of ovarian cancer (OC) and are associated with increased sensitivity to platinum drugs and new target drugs that inhibit proteins of poly(ADP-ribose) polymerase family. The discovery of new therapeutic options in the treatment of patients with...
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| Format: | Article |
| Language: | Russian |
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IP Habib O.N.
2017-01-01
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| Series: | Современная онкология |
| Subjects: | |
| Online Access: | https://modernonco.orscience.ru/1815-1434/article/viewFile/27116/pdf |