Sparc: a sparsity-based consensus algorithm for long erroneous sequencing reads

Motivation. The third generation sequencing (3GS) technology generates long sequences of thousands of bases. However, its current error rates are estimated in the range of 15–40%, significantly higher than those of the prevalent next generation sequencing (NGS) technologies (less than 1%). Fundament...

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Bibliographic Details
Main Authors: Chengxi Ye, Zhanshan (Sam) Ma
Format: Article
Language:English
Published: PeerJ Inc. 2016-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2016.pdf