Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir. Omeprazole did not affect the antiviral effects of ribavirin in non-toxic concentrations up to 80 μg/mL but...

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Bibliographic Details
Main Authors: Martin Michaelis, Malte C. Kleinschmidt, Denisa Bojkova, Holger F. Rabenau, Mark N. Wass, Jindrich Cinatl Jr.
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
HSV
HSV-1
HSV-2
antiviral therapy
antiviral drugs
ribavirin
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02790/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02790/full

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