Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex

Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex

The axon initial segment (AIS) is critical for action potential initiation and implicated in the regulation of neuronal excitability. The authors describe bidirectional AIS plasticity in a behaviourally relevant context, revealing that the AIS acts in vivo as a homeostatic regulatory domain.

Bibliographic Details
Main Authors: Nora Jamann, Dominik Dannehl, Nadja Lehmann, Robin Wagener, Corinna Thielemann, Christian Schultz, Jochen Staiger, Maarten H. P. Kole, Maren Engelhardt
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20232-x

Internet

https://doi.org/10.1038/s41467-020-20232-x

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