Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in Drosophila Sensory Neurons.

During development, certain Drosophila sensory neurons undergo dendrite pruning that selectively eliminates their dendrites but leaves the axons intact. How these neurons regulate pruning activity in the dendrites remains unknown. Here, we identify a coiled-coil protein Spindle-F (Spn-F) that is req...

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Bibliographic Details
Main Authors: Tzu Lin, Po-Yuan Pan, Yu-Ting Lai, Kai-Wen Chiang, Hsin-Lun Hsieh, Yi-Ping Wu, Jian-Ming Ke, Myong-Chol Lee, Shih-Sian Liao, Hsueh-Tzu Shih, Chiou-Yang Tang, Shi-Bing Yang, Hsu-Chen Cheng, June-Tai Wu, Yuh-Nung Jan, Hsiu-Hsiang Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4634852?pdf=render