Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis

Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Globally, tuberculosis is second only to AIDS in mortality and the disease is responsible for over 1.3 million deaths each year. The impractically long treatment schedules (generally 6–9 months) and unpleasant side effects o...

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Bibliographic Details
Main Authors: Sherry L. Mowbray, Muthu K. Kathiravan, Abhishek A. Pandey, Luke R. Odell
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
tuberculosis
glutamine synthetase
drug discovery
structure-activity relationship
Mycobacterium tuberculosis
Online Access:http://www.mdpi.com/1420-3049/19/9/13161

Internet

http://www.mdpi.com/1420-3049/19/9/13161

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