PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnthigh Metastatic Colon Cancer Cells

PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnthigh Metastatic Colon Cancer Cells

The Wnt pathway is abnormally activated in the majority of colorectal cancers, and significant knowledge has been gained in understanding its role in tumor initiation. However, the mechanisms of metastatic outgrowth in colorectal cancer remain a major challenge. We report that autophagy-dependent me...

Full description

Bibliographic Details
Main Authors: Simone Ragusa, Jianpin Cheng, Konstantin I. Ivanov, Nadine Zangger, Fatih Ceteci, Jeremiah Bernier-Latmani, Stavros Milatos, Jean-Marc Joseph, Stephane Tercier, Hanifa Bouzourene, Fredrik T. Bosman, Igor Letovanec, Giancarlo Marra, Michel Gonzalez, Patrizia Cammareri, Owen J. Sansom, Mauro Delorenzi, Tatiana V. Petrova
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007177

Internet

http://www.sciencedirect.com/science/article/pii/S2211124714007177

Similar Items