Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs).

Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs).

Multipotent mesenchymal stem cells (MSCs) can undergo self-renewal and give rise to multi-lineages under given differentiation cues. It is frequently desirable to achieve a stable and high level of transgene expression in MSCs in order to elucidate possible molecular mechanisms through which MSC sel...

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Bibliographic Details
Main Authors: Sheng Wen, Hongmei Zhang, Yasha Li, Ning Wang, Wenwen Zhang, Ke Yang, Ningning Wu, Xian Chen, Fang Deng, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Guolin Zhou, Hue H Luu, Rex C Haydon, Lewis L Shi, Tong-Chuan He, Guanghui Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979777?pdf=render

Internet

http://europepmc.org/articles/PMC3979777?pdf=render

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