Metformin strengthens uroepithelial immunity against E. coli infection

Abstract Urinary tract infection frequently caused by E. coli is one of the most common bacterial infections. Increasing antibiotic resistance jeopardizes successful treatment and alternative treatment strategies are therefore mandatory. Metformin, an oral antidiabetic drug, has been shown to activa...

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Bibliographic Details
Main Authors: Rakesh Kumar Majhi, Soumitra Mohanty, Witchuda Kamolvit, John Kerr White, Andrea Scheffschick, Hanna Brauner, Annelie Brauner
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98223-1