3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.

3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.

3,3'Diindolylmethane (DIM), a natural phytochemical, has shown inhibitory effects on the growth and migration of a variety of cancer cells; however, whether DIM has similar effects on vascular smooth muscle cells (VSMCs) remains unknown. The purpose of this study was to assess the effects of DI...

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Bibliographic Details
Main Authors: Hongjing Guan, Lihua Zhu, Mingyue Fu, Da Yang, Song Tian, Yuanyuan Guo, Changping Cui, Lang Wang, Hong Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323601?pdf=render

Internet

http://europepmc.org/articles/PMC3323601?pdf=render

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