Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits.
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01082-6 |
Summary: | The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits. |
---|---|
ISSN: | 2041-1723 |