Computational design of small transcription activating RNAs for versatile and dynamic gene regulation
The structural basis of RNA-based gene control offers the possibility of de novo design. Here the authors present a computational design approach for Small Transcription Activating RNAs a bacterial RNA regulator that allows for versatile and dynamic control of genes, pathways and genetic circuits.
Main Authors: | James Chappell, Alexandra Westbrook, Matthew Verosloff, Julius B. Lucks |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01082-6 |
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